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    Cortisol and DHEA Testing: Understanding Stress-Related Health Beyond “Not Getting Enough Rest”

    2 minute(s) read
    Information by
    Dr. Napawon Poonyavejthumrong
    Dr. Napawon Poonyavejthumrong

    Bangkok Hospital Chiang Rai

    Updated on: 24 Jul 2026
    Dr. Napawon Poonyavejthumrong
    Dr. Napawon Poonyavejthumrong
    Bangkok Hospital Chiang Rai
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    Cortisol and DHEA Testing: Understanding Stress-Related Health Beyond “Not Getting Enough Rest”
    Bangkok Hospital Chiang Rai
    Updated on: 24 Jul 2026

    Today, stress has become a part of everyday life, whether from work, staying up late, insufficient sleep, or accumulated pressure. Chronic stress does not affect only emotional well-being; it can also directly influence the body’s hormonal system.

    One of the key hormones involved in the stress response is cortisol, which is produced by the adrenal glands. Cortisol helps the body remain alert, regulates blood sugar and blood pressure, and supports the body’s response to stress.

    Another important hormone is DHEA, or dehydroepiandrosterone. It is a precursor to several sex hormones and is associated with energy levels, muscle mass, immune function, and physical recovery.

    When the body is exposed to ongoing stress for a prolonged period, the balance of these hormones may be disrupted, potentially resulting in symptoms such as:

    • Fatigue despite getting enough sleep
    • Poor-quality or interrupted sleep
    • Mental fatigue and difficulty concentrating
    • Easy weight gain, especially around the waist
    • Mood swings and irritability
    • Reduced immunity and frequent illness
    • Slow recovery after exercise

    Cortisol and DHEA levels can be measured through blood tests. In some cases, saliva testing at different times of the day may be used to assess hormone patterns throughout the day. These results can help doctors evaluate hormonal balance and understand the possible effects of chronic stress on the body.

    However, the purpose of testing is not simply to determine whether a person is “stressed” or “not stressed.” The results should be considered together with symptoms, medical history, and other health information to support a more comprehensive healthcare plan, which may include:

    • Improving sleep schedules and sleep quality
    • Reducing caffeine or alcohol intake
    • Choosing an appropriate level of exercise without overtraining
    • Practising stress-relieving techniques such as breathing exercises, meditation, or yoga
    • Adjusting nutrition according to the body’s needs

    Good health depends not only on routine blood test results but also on the body’s overall balance and ability to recover. Cortisol and DHEA testing may therefore be another useful tool for understanding how stress affects health and for developing a more targeted approach to self-care.

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