Beware of MIS-A!
Key Things to Know After Recovering from COVID-19
“Adults who have been infected by COVID-19 or who have recovered from it may develop Multisystem Inflammatory Syndrome in Adults (MIS-A) or ‘Long COVID’, which is an inflammatory condition with consequences that can lead to tissue and organ dysfunction throughout the body. It can make symptoms more severe and life-threatening if a patient with such a condition does not obtain treatment in a timely manner.”
Patients must be aware of any abnormal signs or symptoms since the complication can occur between 2 and 12 weeks after the infection and recovery.
Symptoms of MIS-A
- Fever of 38°C or higher 24 hours before admission or within the first 3 days of hospitalization
- A skin rash or bloodshot eyes
- New neurological symptoms such as seizures, lethargy without previous brain disease, or weakness and numbness of the hands and feet
- Low blood pressure or shock not caused by medications or medical procedures
- Abdominal Pain, Diarrhea, Vomiting
- Chest Pain, Dyspnea
- Blood Spots
If you are showing any of the above symptoms, please contact a doctor immediately. As with treatment for MIS-C in children, MIS-A patients are treated with steroids, intravenous immunoglobulin (IVIG), IL-6 receptor antagonists, and other medications or ventilation support as needed.
What to Know About MIS-A
According to Dr. Chanya Chomchoey, MD, a pulmonologist at Bangkok Hospital Chiang Mai, MIS-A is an inflammatory disorder in the multiorgan system usually found in individuals aged 21 and up. The inflammatory response is believed to be triggered by a COVID-19 infection.
The CDC defines MIS-A as a condition found in patients aged 21 or older, hospitalized for 24+ hours or with a condition resulting in death, with no alternative diagnosis like bacterial sepsis or chronic disease exacerbation.
MIS-A Diagnosis
- Increased inflammatory levels in the body
- Positive SARS-CoV-2 test via RT-PCR, serology, or antigen test
Doctor Suggestions:
Dr. Chanya suggests that avoiding COVID-19 infection is the best way to prevent MIS-A. Patients who contract COVID-19 should follow their doctor’s advice and monitor for unusual symptoms.
“Even though MIS-A incidence is lower than MIS-C and not all adult patients develop MIS-A complications, patients should not ignore signs or symptoms after COVID-19 recovery. The best protection is still avoiding infection and exposure.”
References
- Patel P et al. Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults: A Systematic Review. JAMA Netw Open. 2021;4(9)
- Belay ED et al. Multisystem Inflammatory Syndrome in Adults after SARS-CoV-2 Infection and COVID-19 Vaccination. Clin Infect Dis. 2021 Nov 28
- Ahmad F et al. Multisystem inflammatory syndrome in adults: A rare sequela of SARS-CoV-2 infection. Int J Infect Dis. 2021 Jul;108:209–211.
Dr. Chanya Chomchoey
A pulmonologist
Long COVID Center | Bangkok Hospital Chiang Mai
