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    Rabies Prevention

    2 minute(s) read
    Information by
    Bangkok Hospital Phitsanulok
    Updated on: 20 Jun 2025
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    Rabies Prevention
    Bangkok Hospital Phitsanulok
    Updated on: 20 Jun 2025

    Rabies: A Deadly Yet Preventable Disease

    Rabies is a life-threatening viral disease that is almost always fatal once clinical symptoms appear. However, it is entirely preventable through prompt and appropriate medical care. The rabies virus is transmitted from animals to humans primarily through the saliva of infected animals—most commonly via bites, scratches, or saliva contact with broken skin or mucous membranes. Understanding proper preventive measures and timely treatment can truly save lives.

    What Is Rabies?
    Rabies is caused by the Rabies virus, which affects the central nervous system (CNS) of mammals, including humans. Once the virus enters the body, it travels along peripheral nerves toward the brain, where it induces encephalitis, often resulting in death.

    Modes of Transmission
    Rabies is transmitted to humans through:

    • Bites from infected animals

    • Licking of open wounds or mucous membranes (eyes, mouth, or nose) by an infected animal

    • Scratches or contact with claws contaminated with infected saliva

    Common Animal Vectors Include:

    • Dogs (the most common source globally)

    • Cats

    • Bats

    • Wild animals such as foxes, raccoons, and monkeys

    Clinical Stages of Rabies in Humans

    Rabies symptoms typically progress through three main stages:

    1. Incubation Period

    • Usually lasts 1 to 3 months (but can range from 1 week to over a year)

    • No symptoms are present during this stage

    2. Prodromal Stage

    • Fever, fatigue

    • Headache

    • Pain or itching at the site of the bite (a hallmark symptom)

    • Behavioral changes such as anxiety or irritability

    3. Neurological Stage

    • Hydrophobia (fear of water) and difficulty swallowing

    • Aerophobia (fear of drafts or air movement), hypersensitivity to light and sound

    • Excessive salivation

    • Seizures, respiratory distress, and loss of consciousness

    • Once neurological symptoms appear, the disease is almost invariably fatal

    Rabies Prevention Measures

    1. Vaccination of Pets

    • Dogs and cats should receive rabies vaccinations annually

    • Keep pets in secure areas and avoid contact with stray or wild animals

    2. Avoiding Contact with Unknown Animals

    • Refrain from handling stray dogs or cats

    • Avoid interaction with wild animals

    3. Immediate Wound Care After Exposure

    • Wash the wound thoroughly with soap and running water for at least 15 minutes

    • Apply an antiseptic such as Povidone-Iodine

    • Seek medical attention immediately for post-exposure prophylaxis

    Post-Exposure Management

    If bitten or scratched by a potentially rabid animal, the following steps are critical:

    1. Immediate Wound Cleansing

    • Wash the wound thoroughly with soap and water

    • Apply appropriate antiseptics

    2. Rabies Post-Exposure Prophylaxis (PEP)

    • Administer the rabies vaccine on days 0, 3, 7, 14, and 28

    • In severe exposures (e.g., deep wounds or bites on the head, neck, or hands), administer Rabies Immunoglobulin (RIG) in addition to the vaccine

    3. Observation of the Animal

    • If the biting animal is a domestic pet, observe it for 10 days

    • If the animal shows signs of illness or dies, notify a veterinarian and local public health authorities immediately

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